Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, Travel Tumbler is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization.Through its interaction with other proteins, Rap1 plays many roles during cell invasion and metast
BackgroundFibrinogen is an essential hemostatic factor and cardiovascular disease risk factor.Early attempts at evaluating the causal effect of fibrinogen on coronary heart disease (CHD) and myocardial infraction (MI) using Mendelian randomization (MR) used single variant approaches, and did not take advantage of recent genome-wide association stud
Purpose: To present the clinical, histological, and radiographic findings of a case of orbital myofibroma in an unusual location.The literature is reviewed and the clinical relevance discussed.Methods: A 5-year-old boy was examined with Shawl a 1.5-month history of progressive swelling in the left supraorbital region.Results: Examination revealed a
Nano-drug delivery systems (NDDS) are functional drug-loaded nanocarriers widely applied in cancer therapy.Recently, layer-by-layer (LbL) assembled NDDS have been demonstrated as one of the most promising platforms in delivery of anticancer therapeutics.Here, a brief review of the LbL assembled NDDS One Hitters for cancer treatment is presented.The